Article Abstract:
High molecular mass proteins present in the outer membrane of Escherichia coli VU3695 and Halomonas MAC make the bacterial cells resistant to high concentrations of formaldehyde. These proteins are either absent or present in low concentrations in formaldehyde sensitive mutants. The resistance is not due to formaldehyde dehydrogenase, as high levels of the enzyme are unable to make the cells formaldehyde-tolerant. Treatment of the cells with EDTA has no effect on formaldehyde dehydrogenase but increases sensitivity to formaldehyde probably by increasing the membrane permeability.
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Article Abstract:
The transcriptional characterization of the regulatory system that controls the inducible expression of pco-encoded copper resistance was reported. The two copper-dependent promoters found within the pco determinant were PpcoA and PpcoE, which both differ in structure and relative activity. The pco-encoded copper resistance system was seen as an auxiliary copper control mechanism for the cell.
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Article Abstract:
The transcript level of several genes involved in the transposition of IS elements was increased in E. coli exposed to toxic levels of Zn(II), Cd(II), Co(II), and Ni(II). In particular, insA gene expression increased. This gene may be involved in metal tolerance.
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