Identification and distinct regulation of yeast TATA box-containing genes

Article Abstract:

Approximately 20% of yeast genes that contain a TATA box are associated with response to stress, are highly regulated, and preferentially utilized saga rather than TFID when compared to TATA-less promoters. Transcriptional regulation in yeast appears to be mechanistically bipolar that possibly reflects the need to balance inducible stress-related responses with constitutive housekeeping functions.

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A role for TFIIIC transcription factor complex in genome organization

Article Abstract:

Inverted repeat (IR) boundary elements lying the fission yeast mating-type heterochromatin domain contain B-box sequences that prevent heterochromatin from spreading into neighboring euchromatic regions by recruiting transcription factor TFIIIC complex without RNA polymerase III. An analysis conducted brings out a general genome organization mechanism involving conserved TFIIIC complex.

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Cdk 1-dependent regulation of the mitotic inhibitor Wee1

Article Abstract:

The direct regulation of the budding-yeast homolog of Wee1, Swe1, by cyclin-dependent kinase 1 (Cdk1) is discussed. The regulation of Swe1-Cdk1 complex plays an important role in controlling the transition into mitosis.

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