Hypothesis: Compositional complementarily and prebiotic ecology in the origin of life

Article Abstract:

The emergence of life from simple constituents, emphasizing a general process based on physical principles and physicochemical constraints rather than particular chemistries of chemical components is discussed. Each composome species had a particular molecular composition resulting from molecular complementarily among environmentally available prebiotic compounds.

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DNA replication and models for the origin of piRNAs

Article Abstract:

The piRNA class of small RNAs is distinct from other small RNAs due to their nucleotide size, single-strandedness and the clustered arrangement of their origins, reminiscent of the mechanisms of DNA replication. Three models are presented to indicate that the origin of piRNAs might be mechanistically similar to key processes in DNA replication.

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Ion condensation and signal transduction

Article Abstract:

The operation of the process of ion condensation in signal transduction is investigated. The use of macromolecular network as an integrative receptor is discussed.

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