Homologous recombination as the main mechanism for DNA integration and cause of rearrangements in the filamentous ascomycete Ashbya gossypii

Article Abstract:

Transformations of DNA in the fungus Ashbya gossypii revealed that the rearrangements between inverted and direct repeats present in the plasmid are homologous. Studies on many filamentous ascomycetes have shown a number of transforming DNA routes and some posttransformational alterations. The observations in Ashbya gossypii are rare and transformations with five constructs exhibit integration at the homologous locus with a background of nonhomologous recombination.

author: Philippsen, Peter, Steiner, Sabine, Wendland, Jurgen, Wright, Martin C.
Analysis, Genetic recombination

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A space-time process model for the evolution of DNA sequences

Article Abstract:

The newly developed model for the evolution of DNA sequences by substitution of nucleotides reveals that a large variation of rates exists among the nucleotide sites in the sequence. The model assumes that the nucleotide sites evolve over a period of time and that the substitution rates are related to the sites. The substitution rates at sites adjacent to each other are influenced by the rates at the nearby sites.

author: Ziheng Yang
DNA sequencers

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Stability of tandem repeats in the Drosophila melanogaster Hsr-omega nuclear RNA

Article Abstract:

A nuclear ribonuclic acid with more than 5 kb of tandem repeat sequences is produced by the Drosophila melanogaster Hsr-omega locus. These locus have peculiar characteristics and exhibit concerted evolution identical to the of the classical satellite DNAs. The monomer is a 280 binding protein and exhibit differences in the single nucleotide sequences.

author: Hogan, N.C., Slot, F., Traverse, K.L., Garbe, J.C., Bendena, W.G., Pardue, M.-L.
RNA, Drosophila

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subjects list: Research, DNA
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