The binding pattern of two carbohydrate-binding modules of laminarinase Lam16A from Thermotoga neapolitana: differences in beta-glucan binding within family CBM4

Article Abstract:

Research shows that family of carbohydrate-binding modules, comprising complex hydrolytic extracellular bacterial enzymes, possess different polysaccharide-binding specificities. Two modules flank Laminarinase Lam16A from Thermotoga nepolitana, which bind to different glucan molecules such as soluble laminarin and barley glucan at the N-terminus and curdlan, pustulan and yeast glucan at the C-terminus.

author: Zverlov, Vladimir V., Volkov, Ilia Y., Velikodvorskaya, Galina A., Schwartz, Wolfgang H.
Statistical Data Included, Microbiological synthesis, Microbial polysaccharides, Protein binding, Bacterial cell walls

User Contributions:

Comment about this article or add new information about this topic:

CAPTCHA

Lic16A of Clostridium thermocellum, a non-cellulosomal, highly complex endo-beta-1,3-glucanase bound to the outer cell surface

Article Abstract:

Research has been conducted on Clostridium thermocellum which produced beta-1,3-glucanase. The authors report that Lic16A protein has been located on the cell surface, and that its production allowed C. thermocellum to grow on beta-1,3- or beta 1,3-1,4-glucan.

author: Zverlov, Vladimir V., Velikodvorskaya, Galina A., Lottspeich, Friedrich, Fuchs, Klaus-Peter, Schwarz, Wolfgang H.
Science & research, Research, Genetic aspects, Cells (Biology), Growth, Clostridium, Microbiology, Cells, Genetic research, Company growth

User Contributions:

Comment about this article or add new information about this topic:

CAPTCHA

Highly thermostable endo-1,3-beta-glucanase (laminarase) LamA from Thermotoga neapolitana: nucleotide sequence of the gene and characterization of the recombinant gene product

Article Abstract:

The primary structure of the gene and the LamA protein of Thermotoga neapolitana was analyzed to determine the relationship between 1,3-beta- and 1,3-1,4-beta-glucanases. Analysis of the purified recombinant LamA protein fractions from Thermotoga neapolitana indicated the presence of enzymatic and purification profiles that were similar to the 52 kilodalton (kDa) glucanase. The purified 52 kDa beta-glucanase also resembled the processed form of the 73 kDa recombinant LamA which exhibited high specificity towards laminarin.

author: Zverlov, Vladimir V., Volkov, Ilia Y., Schwarz, Wolfgang H., Velikodvorskaya, Tatjana V.
Nucleotide sequence, Base sequence, Microbial enzymes

User Contributions:

Comment about this article or add new information about this topic:

CAPTCHA


subjects list: Germany, Physiological aspects, Russia, Glucans, Analysis, Bacterial proteins
This website is not affiliated with document authors or copyright owners. This page is provided for informational purposes only. Unintentional errors are possible.