High-level genotypic variation and antibiotic sensitivity among Escherichia coli O157 strains isolated from two Scottish beef cattle farms

Article Abstract:

The characterization and population genetics of Escherichia coli O157 in a series of longitudinal studies of cattle on two farms in Scotland is studied in detail and reported. Results showed a high variation among strains of E.coli in just two farms in the same vicinity over a 2-year period. The studies demonstrated resistance of the strains to sulfamethoxazole, chloramphenicol and at a lower rate, other antibiotics, indicating the preservation of antibiotic sensitivity in a rapidly changing population of E.coli O157.

author: Vali, Leila, Pearce, Michael C., Wisely, Karen A., Turner, Esther J., Knight, Hazel I., Smith, Alastair W., Amyes, Sebastian G. B.
Genotype, Genotypes, Genetic variation

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Age-related decline in carriage of ampicillin-resistant Escherichia coli in young calves

Article Abstract:

Comparison of the carriage of ampicillin-resistant Escherichia coli with age and time in multiple cohorts of calves sampled monthly from birth on four farms is done. The presence of ampicillin-resistant E.coli in older cattle on all farms suggests that in some calves the decline is transient, with cattle reacquiring resistant bacteria at a later point due to environmental changes or management events on the farm.

author: Pearce, Michael C., Knight, Hazel I., Hoyle, Deborah V., Shaw, Darren J., Davison, Helen C., Low, J. Chris, Gunn, George J., Woolhouse, Mark E.J.
Cohort analysis, Ampicillin

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Molecular epidemiology of antimicrobial-resistant commensal Escherichia coli strains in a cohort of newborn calves

Article Abstract:

A unique view of the microbial ecology of an antimicrobial-resistant commensal Escherichia coli population within a large cohort of calves monitored intensively from birth is presented. Results reveal that calves are colonized by a succession of multiply resistant strains, with a probable environmental source, that disseminated through the cohort over time.

author: Turner, Esther J., Hoyle, Deborah V., Low, J. Chris, Gunn, George J., Amyes, Sebastian G.B., Yates, Catherine M., Chase-Topping, Margor E., Woolhouse, Mark E., Davies, Sarah E.
Livestock, Except Dairy and Poultry, Epidemiology, Calves, Calves (Cattle)

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subjects list: Research, Genetic aspects, Escherichia coli
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