Helicobacter pylori physiology predicted from genomic comparison of two strains

Article Abstract:

A study was conducted to compare the two genomic strains of the pathogenic bacteria Helicobacter pylori strains J99 and 26695. Analysis of the genomic strains revealed that even though the chromosomes are organized differently in a limited number of discrete regions, the genome size, genetic content and gene order of the two strains have been found to be remarkably similar. Findings have indicated that strain-specific genes that encode proteins with an assigned function have been predicted to have little impact on the physiology of H. pylori.

author: Brown, Eric D., Trust, Trevor J., Mills, Scott D., Alm, Richard A., Guild, Braydon C., Noonan, Brian, Moir, Donald T., Carmel, Gilles, Uria-Nickelsen, Maria, Vovis, Gerald F., Doig, Peter, Jonge, Boudewijn L. de, Tummino, Peter
Genetic aspects, Gene expression, Genomes, Helicobacter pylori

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Recombinant infectious hematopoietic necrosis virus and viral hemorrhagic septicemia virus glycoprotein epitopes expressed in Aeromonas salmonicida induce protective immunity in rainbow trout (Oncorhynchus mykiss)

Article Abstract:

Vaccination of rainbow trout with a strain of the bacterium Aeromonas salmonicida containing genes for glycoproteins produced by viral hemorrhagic septicemia virus and infectious hematopoietic necrosis virus confer on the fish an immunity against the viruses. The viral genes were inserted into the A440 strain of this bacterium, which unlike other strains, does not cause furunculosis in fish. When the vaccinated fish cohabitated with fish infected with the viruses, they did not become infected.

author: Trust, Trevor J., Noonan, Brian, Enzmann, Peter J.
Prevention, Observations, Virus diseases, Immunity, Immunity (Physiology), Vaccines, Rainbow trout, Furunculosis

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Detection of Aeromana salmonicida from fish by using polymerase chain reaction amplification of the virulence surface array protein gene

Article Abstract:

The application of polymerase chain reaction in detecting Aeromonas salmonicida from infected fishes is discussed. The analysiswas facilitated by direct detection from samples after a bacterial outgrowth step. The assay was found to be sensitive enough to be used as a noninvasive method for monitoring fish populations for the presence of carrier fish, besides being highly reproducible.

author: Thomas, Connor J., Gustafson, Corrine E., Trust, Trevor J.
Identification and classification, Polymerase chain reaction

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subjects list: Research, Bacteria, Pathogenic, Pathogenic bacteria, Usage
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