Hearts and bones: shared regulatory mechanisms in heart valve, cartilage, tendon, and bone development

Article Abstract:

A study to understand the specific regulatory pathways that help in the heart valve development along with the development of cells in connective tissues like cartilage, tendon, and bones, is presented.

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NFATc1 expression in the developing heart valves is responsive to the RANKL pathway and is required for endocardial expression of cathepsin K

Article Abstract:

Role of nuclear factor of activated T-cells in heart valve leaflet morphogenesis and endocardial expression of receptor activator of NF?B ligand is presented.

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BMP and FGF regulatory pathways control cell lineage diversification of heart valve precursor cells

Article Abstract:

Regulation of heart valve progenitor cell diversification by fibroblast growth factor 4 and bone morphogenetic protein 2 is analyzed.

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