Growth patterns of the heart and kidney suggest inter-organ collaboration in facultative fetal growth

Article Abstract:

Thirty-four healthy maternal and fetal pairs of 24 nonsmokers and 10 smokers participated in a longitudinal growth study from the thirteenth week of pregnancy to document fetal kidney and heart growth trajectories and morphology. The results suggest that cell-level adaptive responses to hypoxia and chemical insults are operative and illustrate the importance of longitudinal ultrasound to directly assess the organ-level growth response of the human fetus to a prenatal stress, in lieu of birth outcome measures.

author: Lampl, Michelle, Jeanty, Philippe, Kuzawa, Christopher W.
Risk factors, Kidney diseases, Fetal heart, Smoking in pregnancy

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Cellular life histories and bow tie biology

Article Abstract:

In order to consider the dynamic nature of fetal growth, the explanatory framework developed in nonlinear dynamics, known as the 'bow tie', is presented as a useful paradigm in a study of cellular life histories. The approach has implications for robust and inventive approaches to cell, organ, and whole organism construction.

author: Lampl, Michelle
Research and Development in the Physical, Engineering, and Life Sciences, Cellular Biology, Fetus, Cytology, Fetal development, Human biology

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Child factor in measurement dependability

Article Abstract:

This article discusses methods of measuring child growth, including sources of component errors.

author: Lampl, Michelle, Birch, Leann, Picciano, Mary Frances, Johnson, Michael L., Frongillo, Edward A., Jr.
Analysis, Growth, Growth (Physiology), Child development

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subjects list: Research, United States
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