Grasping human transcriptome evolution: What does it all mean?

Article Abstract:

A study exploring broad evolutionary patterns for thousands of genes by comparing them between humans and chimpanzees both in terms of expression level and protein-coding sequence concludes that genes evolve in both these dimensions in parallel as a function of their tissue environment. A discussion on the limitations of this and other similar analyses is presented.

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Out of the dog house: the emergence of the canine genome

Article Abstract:

An attempt is made to review the recent progress in the genome sequencing of the dog and discuss new discoveries based on its comparison to mouse and human. Also, current efforts to complete the dog genome and the promise that this holds for comparative genomic and evolutionary studies are overviewed.

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Mining the crucial 1%

Article Abstract:

The human genome is estimated to be about 99% identical at the nucleotide level to that of the closest human relative, the chimpanzee. The search for the biological basis of uniquely human characteristics thus focuses on only about 1% of the human genome.

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