Glucosaminidase of Bacillus subtilis: cloning, regulation, primary structure and biochemical characterization

Article Abstract:

The glucosaminidase, produced by Bacillus subtilis AC327, is a 90 kDa protein containing direct repeats which are the cell wall binding regions. Loss of these repeats decreases the lytic ability of the protein. The lytD gene, encoding the protein, consists of a monocistronic operon containing a signal peptide. The lytD gene is expressed during the exponential growth phase and dissolves the bacterial cell wall of the cell expressing it. The expression of lytD decreases in the presence of a null mutation in sigD.

author: Mori, Masao, Rashid, Muhammad H., Sekiguchi, Junichi
Observations, Bacillus subtilis, Amino acid sequence, Amino acid sequencing

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A low-molecular-mass protein from Methylococcus capsulatus (Bath) is responsible for the regulation of formaldehyde dehydrogenase activity in vitro

Article Abstract:

A study was conducted to analyze a low-molecular-mass protein from Methylococcus capsulatus that influences the regulation of formaldehyde dehydrogenase activity in vitro. Substrate specificity was determined during the presence and absence of modifin for a range of aldehydes and alcohols. High performance liquid chromatography was utilized to determine amounts of formate and acetate generated in enzyme assays. Experimental results indicated that the protein supports no activity towards formaldehyde.

author: Dalton, Howard, Tate,, Stephen
Enzymes, Formaldehyde, Dehydrogenases, Oxidoreductases, Aldehydes, Alcohols

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Structure and function of cysBJIH gene cluster in the purple sulphur bacterium Thiocapsa roseopersicina

Article Abstract:

A study was conducted to analyze the characteristics and role of a cysBJIH gene cluster in the sulphur bacterium Thiocapsa roseopersicina. T. roseopersicina was grown phototrophically at 500 lx. Experimental results indicated that the gene cluster supported four structural genes homologous to cysB, CysJI and CysH of enterobacteria. Findings also showed that it encoded a transcriptional regulator protein.

author: Haverkamp, Thomas, Schwenn, Jens D.
Genetic aspects, Sulfur bacteria, Cysteine

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subjects list: Research, Proteins
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