Article Abstract:
A study examined two self-sterile mutations that dictate the spermatogenesis-defective gene spe-17 influences unc-22, and they do not complement each other for Unc-22 and spermatogenesis faults. These mutations are deficiencies (hcDfl and hDfl3) that influence more than one transcription unit. The sequencing of spe-17 DNAs revealed that the deduced 142 amino acid protein sequence is extremely charged and rich in serine and threonine, but exhibits no major homology to any previously identified protein sequence.
User Contributions:
Comment about this article or add new information about this topic:
Article Abstract:
The gene, mog-1, functions as regulator of the sperm/oocyte switch in the hermaphrodite germ line of Caenorhabditis elegans in addition to its role in embryogenesis. The relationship between its roles in the spermatogenesis-oogenesis switch and embryogenesis is investigated. Analysis showed that mog-1 acts in the post-transcriptional regulation of germ-line RNAs. Thus, a loss of mog-1 activates fem-3 and prevents the sperm/oocyte switch.
User Contributions:
Comment about this article or add new information about this topic:
Article Abstract:
The fog-3 gene, which is essential for the differentiation of germ cells into sperms and oocytes, is identified and characterized in Caenorhabditis elegans. It acts on the germ cells at the end of the regulatory hierarchy which controls the germ line sex determination. The sexual identity of tissues near the germ-cells are not affected by the mutations occurring in fog-3.
User Contributions:
Comment about this article or add new information about this topic: