Genes, neurons and codes: remarks on biological communication

Article Abstract:

This article examines how information is stored and processed in the course of organism's development and subsequently in the functioning of central nervous system. Research findings suggest that intercellular communication relies on biological signaling systems such as cellular memory. Data indicate that cellular memory is embodied in anatomy and neurochemistry, which form the major "static" factors routing of neural impulses.

author: Kerszberg, Michel
France, Central nervous system, Cellular signal transduction, Cell interaction, Cell interactions, Developmental neurology

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Reconstructing eukaryotic NAD metabolism

Article Abstract:

Research findings indicate that the development of several nicotinamide adenine dinucleotide (NAD) biosynthetic routes during evolution leading to NAD synthesis. Results point out that three distinct precursors are involved in the biosynthetic process and that the multiple metabolic routes in higher eukaryotes may be the result of differences in tissue distribution and/or intracellular compartmentalization of NAD metabolism.

author: Rongvaux, Anthony, Andris, Fabienne, Gool, Frederic Van, Leo, Oberdan
Belgium, Metabolic regulation, Enzyme regulation, Coenzymes, NAD (Coenzyme), Nicotinamide adenine dinucleotide

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Hypothalamic fatty acid metabolism: A housekeeping pathway that regulates food intake

Article Abstract:

Hypothalamus, a specialized area in the brain, integrates the control of energy homeostatis and circulating long-chain fatty acids act as signals of nutrient surplus in the hypothalamus. Hypothalamic fatty acid metabolism and the physiological regulation of feeding by the pathway are reviewed providing directions for future research.

author: Vidal-Puig, Antonio, Lopez, Miguel, Lelliott, Christopher J.
United States, Health aspects, Genetic aspects, Obesity, Hypothalamus, Homeostasis, Fatty acid metabolism

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subjects list: Research, Physiological aspects
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