Genes and mechanisms related to RNA interference regulate expression of the small temporal RNAs that control C. elegans developmental timing

Article Abstract:

Research has been conducted on the gene silencing phenomenon RNAi which can be triggered by the double-stranded RNA. The inactivation of genes related to the RNAi pathway genes has been carried out and the heterochronic phenotypes produced by this inactivation have been examined and discussed.

author: Ruvkun, Gary, Pasquinelli, Amy E., Parrish, Susan, Fire, Andrew, Grishok, Alla, Conte, Darryl, Li, Na, Ilho Ha, Baillie, David L., Mello, Craig C.
South Korea, Canada, Gene expression, RNA, Phenotype, Phenotypes

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On the role of RNA amplification in dsRNA-triggered gene silencing

Article Abstract:

Research has been conducted on the trigger RNA amplification. The effect of this amplification on the RNA interference in Caenorhabditis elegans has been investigated and the results indicate that the amplification mechanism augments the RNA interference-based surveillance potency.

author: Sijen, Titia, Fleenor, Jamie, Simmer, Femke, Thijssen, Karen L., Parrish, Susan, Timmons, Lisa, Plasterk, Ronald H. A., Fire, Andrew
Netherlands, Carrier proteins, Transport proteins, Brain research

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The double life of ribosomal proteins

Article Abstract:

The author discusses the study of ribosomal proteins which are part of cellular response to interferon. The topics include the analysis of ribosomal proteins' ability to inhibit and bind specific mRNA translation.

author: Zimmermann, Robert A.
Biological Product (except Diagnostic) Manufacturing, Biological products exc. diagnostic, Interferon, Cells (Biology), Cells, Polypeptides, Molecules, Ribosomal proteins

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subjects list: Statistical Data Included, United States, Analysis, Physiological aspects, Genetic aspects, Caenorhabditis elegans, Cell research, Cytological research, Messenger RNA, Genetic translation, Translation (Genetics)
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