Farnesol-induced growth inhibition in Saccharomyces cerevisiae by a cell cycle mechanism

Article Abstract:

A study was conducted to analyze the inhibition of the growth of Saccharomyces cerevisiae in medium supporting 25 mu-M farnesol. The farnesol-treated cells were depicted by a transition from budded to unbudded phase and loss of intracellular diacylglycerol. An interference supporting a phosphatidylinositol-type signaling associated with cell cycle progression was proposed as a factor for farnesol-induced growth inhibition in the cells.

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Polycations increase the permeability of Mycobacterium vaccae cell envelopes to hydrophobic compounds

Article Abstract:

Research has been conducted on the Mycobacterium vaccae treated with the polycationic compound sat subinhibitory concentrations. Results indicate that M. vaccae has performed the intracellular degradation of the beta-sitosterol side chain and has exhibited susceptibility to the antimycobacterial agents.

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Disruption of adhC reveals a large duplication in the Mycobacterium smegmatis mc (super)2 155 genome

Article Abstract:

Research has been conducted on the disruption of the adhC gene of Mycobacterium smegmatis. Results demonstrate the existence of the gene copies within the large duplication of the M. smegmatis mc (super)2 155 genome.

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