Expression of the met/hepatocyte growth factor/scatter factor receptor and itsligand during differentiation of Murine P-19 embryonal carcinoma cells

Article Abstract:

Researchers examined the expression of the met proto-oncogene/hepatocyte growth factor (HGF)/scatter factor receptor (SFR), and HGF/SF during differentiation of the pluripotent P19 murine embryonal carcinoma cell line in culture. Their aim was to discover the specific differentiated cell types that expressed the met/HGF/SFR, and to examine the biological purpose of this receptor and its ligand in initial murine development.

author: Xiu-Ming Yang, Morag Park
Growth, Liver cells, Hepatocytes, Mouse leukemia complex

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Neurogenic cells inhibit the differentiation of cardiogenic cells

Article Abstract:

Neurogenic cells possibly isolate molecules necessary for the differentiation of cardiogenic cells rather than produce inhibitory molecules. The study also speculates the probable molecular mechanism which takes part in the phenomenon. Studies on the mechanism of expression of these homeogenes are affected by various experimental circumstances and will help in elucidating the molecular bases of heart formation.

author: Climent, Salvador, Sarasa, Manuel, Villar, Jose M., Murillo-Ferrol, Narciso L.
Research, Neurogenetics, Heart cells

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TAF4b, a TBP associated factor, is required for oocyte development and function

Article Abstract:

Research on female mice null for the TBP associated factor Taf4b shows that infertility is linked to defects in oocyte maturation, zygotic cleavage, and early follicle formation. Genetic and physiological processes are described.

author: Falender, Allison E., Richards, JoAnne S., Shimada, Masayuki, Lo, Yuet K.
Reports, Physiological aspects, Embryology, Experimental, Embryological research, Infertility

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subjects list: Genetic aspects
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