Expression of chimeric human transferrin-chloramphenicol acetyltransferase genes in liver and brain of transgenic mice during development

Article Abstract:

The expression of chimeric human transferrin-chloramphenicol acetyltransferase (TF-CAT) transgenes in liver and brain during development was studied in transgenic mice. The onset of TF(0.67)CAT transgene expression in brain was observed between five to ten days after birth, while in liver, it is turned on between ten to 20 days after birth. In addition, the developmental expression pattern of and the level of protein-DNA complex formation by the transgene were assessed.

author: Yan Lu, Cox, Laura A., Herbert, Damon C., Weaker, Frank J., Walter, Christi A., Adrian, Gwen S.
Transferrin

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Defective postnatal development of the male reproductive tract in LGR4 knockout mice

Article Abstract:

The role of leucine-rich repeat-containing G protein-coupled receptor 4 during male reproductive tract development, using knock out mice studies, is presented.

author: Vassart, Gilbert, Mendive, Fernando, Laurent, Patrick, Schoore, Gregory Van, Skarnes, William, Pochet, Roland
Belgium, Cell receptors, Reproductive organs, Male, Male genitalia

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Reduced fertility of female mice lacking CD81

Article Abstract:

Effects of CD81 gene expression on fertility of mice, using gene knock-out studies, are presented.

author: Prenant, Michel, Rubinstein, Eric, Levy, Shoshana, Boucheix, Claude, Ziyyat, Ahmed, Wrobel, Edyta, Wolf, Jean-Philippe, Naour, Francois Le
United States, Infertility

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subjects list: Research, Gene expression, Genetically modified mice
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