Evolution of the mammary gland from the innate immune system?
Article Abstract:
The purpose of the mammary gland is to provide the newborn with coplous amounts of milk, a unique body fluid that has a dual role of nutrition and immunological protection. The results postulated that mammary glands evolved from the innate immune system as xanthine oxidoreductase evolved a dual role in the mammary gland and hence provide new evidence supporting the hypothesis that the nutritional function of the milk evolved subsequent to its protective function.
Publication Name: BioEssays
Subject: Biological sciences
ISSN: 0265-9247
Year: 2006
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Proposal of a novel diabetogenic mechanism involving the serpin PAI-1
Article Abstract:
Elevated levels of the protease inhibitor PAI-1 are well-known molecular markers of the Metabolic Syndrome. A hypothesis is presented those PAI-1 acts as a causative factor in the development of Metabolic Syndrome and its clinical sequelae.
Publication Name: BioEssays
Subject: Biological sciences
ISSN: 0265-9247
Year: 2006
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