Evidence that the rate-limiting step for the biosynthesis of arachidonic acid in Mortierella alpina is at the level of the 18:3 to 20:3 elongase

Article Abstract:

Fatty acid synthesis is regulated separately from fatty acid elongation in the fungus Mortierella alpina,. Fatty acid desaturation and elongation still occur when the fungus is grown on simple fatty acids.

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Biochemical events leading to the diversion of carbon into storage lipids in the oleaginous fungi Mucor circinelloides and Mortierella alpina

Article Abstract:

Research has been conducted on the Mucor circinelloides and Mortierella alpina. The use of these bacteria as the principle model for the oleaginous filamentous fungi is described and the results indicate the difference in the biochemistry of lipid accumulation between oleaginous yeasts and oleaginous filamentous fungi.

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The role of malic enzyme in the regulation of lipid accumulation in filamentous fungi

Article Abstract:

The role of malic enzyme (ME) in regulating lipid accumulation was examined using two filamentous fungi, Mucor circinelloides and Mortierella alpina. The experiment resulted in the positive correlation between ME activity and lipid accumulation. This was verified by the restoration of ME activity in Mr. circinelloides within four hours after the addition of NH4+. The result indicates that decline in ME activity is due to the ME gene's down-regulation.

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