Article Abstract:
Findings of a study on intrinsic differences in heterochromatic domain formation are analyzed. The study employed two variant position effect variegation mutants in Drosophila melanogaster to examine the compaction of DNA stretching in heterochromatin. Results show that the compaction events are independent of each other and conditioned by different components. These events are influenced by variegation enhancer effects on gene compaction.
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Article Abstract:
The dpp-lacZ reporter genes in the rear end region, where dpp activity is repressed, are expressed by mutant clones that do not exhibit invected (inv) and engrailed (en) activity. The extension of this type of expression enables the investigation of the mode of gene expression in the stripes anterior to the anterior posterior regions. The investigation reveals the genetic mechanisms which produce this type of gene expression.
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Article Abstract:
The Drosophila gene argos is characterized by a diffusible inhibitory signalling protein that possesses an EGF-like motif and conditions cell fate in eye development and wing imaginal discs. Dose titration experiments were conducted to identify the argos gene(s) receptors. Genetic analysis revealed bulge, soba and clown gene functions that interacted with argos and with each other.
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