Evaluation of Canine COL4A3 and COL4A4 as Candidates for Familial Renal Disease in the Norwegian Elkhound

Article Abstract:

Findings of one recombinant between COL4A3 and COL4A4 and familial renal disease indicate that these two genes are not likely to be candidates for the disease in Norwegian elkhound dogs. Microsatellites are developed and discussed.

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RAS Gene Hot-Spot Mutations in Canine Neoplasias

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Screening was performed on 11 canine melanomas and 13 fibrosarcomas to determine point mutations in canine neoplasias. Findings regarding the role of RAS genes are compared to current data from other tumor studies.

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Lack of the SOX9 Gene Polymorphism in Sex Reversal Dogs (78,XX; SRY negative)

Article Abstract:

Findings suggest a role of the 5' flanking region of the SOX9 gene in female-to-male canine sex reversal. Data are drawn from research on a miniature pinscher and two American Staffordshire terriers.

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