Erosion from Staphylococcus aureus biofilms grown under physiologically relevant fluid shear forces yields bacterial cells with reduced avidity to collagen

Article Abstract:

The phenotypic attributes of staphylococcus aureus planktonic cells eroding from biofilms with respect to expression of the collagen adhesin, CNA, is studied to investigate the potential role of early detachment in initiating secondary infections. The results have shown that, despite their low levels of CNA expression, Staphylococcus aureus planktonic cells shed from biofilms have retained the capacity for metastatic spread and the initiation of secondary infection.

author: Ymele-Leki, Patrick, Ross, Julia M.
Biological Product (except Diagnostic) Manufacturing, Drugs, Collagen, Structure, Chemical properties, Report

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Effect of protein, polysaccharide, and oxygen concentration profiles on biofilm cohesiveness

Article Abstract:

A membrane-aerated biofilm reactor inoculated with activated sludge which was used to grow mixed-culture biofilms of different ages and thickness also measure protein and polysaccharide concentration within the biofilm depths is presented.

author: Ahimou, Francois, Novak, Paige J., Semmesns, Michael J., Haugstad, Gred
Bacterial proteins

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Immunoglobulins to surface-associated biofilm immunogens provide a novel means of visualization of methicillin-resistant Staphylococcus aureus biofilms

Article Abstract:

Purified, recombinant forms of selected antigens from the methicillin-resistant Staphylococcus aureus (MRSA) and biofilm-upregulated, cell wall-associated proteins are used to create immunoglobulin G (IgG) antibodies.

author: Costerton, William J., Shirtliff, Mark E., Brady, Rebecca A., Leid, Jeff G., Kofonow, Jennifer
Physiological aspects

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subjects list: Research, Staphylococcus aureus, Microbial mats, Bacterial cell walls
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