Endocytosis conducts the cell signaling orchestra

Article Abstract:

Eukaryotic cells use endocytosis to regulate nutrient internalization, signal transduction, and the composition of the plasma membrane. However, a more complex picture is emerging in which endocytic pathways integrate diverse signals, thereby contributing to a higher level of cellular an organismal organization and thus entocytosis and cell signaling are inter-twined in many biological processes, such as cell motility and cell fate determination.

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Heterotrimeric G protein signaling: Getting inside the cell

Article Abstract:

Heterotrimeric G protein alpha subunit functions at the endosome to stimulate a phosphatidylinositol 3-kinase to help yeast respond to mating pheromones. The identification of intracellular G protein effector and establishing its physiological significance in signaling through genetic tests has helped in understanding heterotrimeric G protein signaling.

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Endocytosis and signaling: an inseparable partership

Article Abstract:

The authors review publications on the endocytosis through the clathrin-coated pits. The topics of interest include signaling from endosomes and its relevance, endocytic pathway as a switch-off for receptor signaling and signaling activation by endocytosis.

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