Sequestration of zinc oxide by fimbrial designer chelators

Article Abstract:

A strain of E. coli that can bind zinc could be used to remove heavy metals from soil or water. The type 1 fimbriae on the bacterial surface bind zinc oxide and the protein appears to be a zinc-containing helicase.

author: Kjaergaard, Kristian, Sorensen, Jack K., Schembri, Mark A., Klemm, Per

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Novel Zn(super 2+)-chelating peptides selected from a fimbria-displayed random peptide library

Article Abstract:

Researchers have identified novel zinc-binding peptide sequences in a random peptide library based on the FimH adhesion on the tip of Escherichia coli type 1 fimbriae. These peptides could be expressed in E. coli and used for heavy metal bioremediation or as a chemical sensor for detecting heavy metals in the environment.

author: Kjaergaard, Kristian, Schembri, Mark A., Klemm, Per
Bioremediation

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Elucidation of the antibacterial mechanism of the Curvularia Haloperoxidase system by DNA microarray profiling

Article Abstract:

A novel antimicrobial system, the Curvularia haloperoxidase system, is examined with the aim of elucidating its mechanism of antibacterial action. The Escherichia coli K-12 strain MG1655 is exposed to the enzyme system, causing a temporary arrest of growth.

author: Schembri, Mark A., Klemm, Per, Gram, Lone, Molin, Soren, Hansen, Eva H., Schafer, Thomas
Science & research, Microbiological research, DNA microarrays

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subjects list: Research, Chelating agents, Escherichia coli
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