Duration of division-related events in cleaving sand dollar eggs

Article Abstract:

Researchers analyzed the processes that start and complete the operational period of a stimulus-to-surface contraction, a receptive surface process and a localized surface contractile process in cytokinesis. The regular duration and duration under experimental conditions were compared to determine the character of mechanisms that coordinate the timing and sequence of processes in cytokinesis. The results indicated each element of cytokinesis can function prior to and after its regular active period. therapeutic method of stopping dependence on benzoadiazepines as an option to NMDA antagonism.

author: Rappaport, R., Rappaport, Barbara N.

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Swyer syndrome and 46,XY partial gonadal dysgenesis associated with 9p deletions in the absence of monosomy-9p syndrome

Article Abstract:

Two cases of 46, XY gonadal dysgenesis have been studied using molecular analysis. In one case, a 9p deletion was detected cytogenetically, while in the other case 9p appeared to be normal. In the first patient, the breakpoint was between D9S144 and D9S267, and the rearranged chromosome was of paternal origin. In the second case, the patient with the normal appearing 9p was hemizygous for markers D9S1858 and VLDLR, with a breakpoint possibly 6-8 cM from the telomere, a deletion that could not be observed through ordinary cytogenetic techniques because of the very terminal location.

author: Rappaport, R., Veitia, R.A., Nunes, M., Quintana-Murci, L., Thibaud, E., Jaubert, F., Fellous, M., McElreavey, K., Goncalves, J., Silva, M., Cidade Rodrigues, J., Caspurro, M., Boieiro, F., Marques, R., Lavinha, J.
Abnormalities, Genetic aspects, Sex determination, Genetic, Sex determination (Genetics), Turner syndrome

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Mutations in the Caenorhabditis elegans gene vab-3 reveal distinct roles in fate specification and unequal cytokinesis in an asymmetric cell division

Article Abstract:

In Caenorhabditis elegans, first division cytokinesis of the male-specific post-embryonic blast cell B is unequal, resulting in different fates for the two daughter cells. Mutations in the gene vab-3 in the B cell lineage disrupt the fate of anterior daughter of B, implying that vab-3 acts after lin-17 for B.a fate specification. The additional lin-17 functions in B lineage have been determined using double mutant analysis.

author: Sternberg, Paul W., Chamberlin, Helen M.
Analysis, Mutation (Biology), Mutation, Caenorhabditis elegans, Cell division

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subjects list: Research, Cytokinesis
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