Drosophila PAR-1 and 14-3-3 inhibit bazooka/PAR-3 to establish complementary cortical domains in polarized cells

Article Abstract:

Research demonstrates a direct regulatory interaction between Drosophila PAR-1 kinase and BAZ, which is mediated by 14-3-3 protein. Results indicate that PAR-1 phosphorylates Bazooka/PAR-3 to generate 14-3-3 binding sites. Data suggest that PAR-1/14-3-3 antagonism of Bazooka may the path by which complementary cortical domains are established in polarized cells.

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Control of dendritic branching and tiling by the tricornered-kinase/furry signaling pathway in drosophila sensory neurons

Article Abstract:

Neurons of certain functional groups are known to exhibit tiling of their dendrites. Tricornered (Trc) and kinase and furry (fry) signaling pathway play an important role in patterning dendritic fields.

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Drosophila Dpp morphogen movement is independent of dynamin-mediated endocytosis but regulated by the clypican members of heparan sulfate proteoglycans

Article Abstract:

Decapentaplegic (Dpp) is found to be extracellular. A model in which Dpp moves along the cell surface by restricted extracellular diffusion is developed.

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