Dorsal-ventral patterning genes restrict NK-2 homeobox gene expression to the ventral half of the central nervous system in Drosophila embryos

Article Abstract:

The expression of the NK-2 homeobox gene in the Drosophila embryo is regulated by the expression of genes which determine the ventral-dorsal and anterior-posterior axis of the embryo. During the blastoderm stage, NK-2 is stimulated in the ventral region by the dorsal protein and in the posterior region by the twist gene independently or along with the dorsal protein. The determination of the boundaries of the neuroectodermal cells expressing NK-2 is independent. The mesodermal lateral neuroectodermal and dorsal epidermal anlage and the mesectodermal cells do not express the NK-2 gene.

User Contributions:

Comment about this article or add new information about this topic:

Comment:  (50-4000 characters)

Name:

E-mail:

Security Code:

A novel homeobox cluster expressed in repeated structures of the midgut

Article Abstract:

The LOX-3 gene cluster is expressed in the midgut of leech embryos and controls the morphogenesis and cellular differentiation of the midgut. The expression of this gene is restricted to the 12 transverse rows of cells present in the area which later forms the crop diverticula. LOX-3 contains the Lox3A, Lox3B and Lox3C homeobox genes in direct tandem repeats. One of the transcripts encoded by Lox3C is present in embryo and adult guts but the other is present only in embryos. The amino acid sequence and the localized expression of LOX-3 is similar in leeches and vertebrates.

User Contributions:

Comment about this article or add new information about this topic:

Comment:  (50-4000 characters)

Name:

E-mail:

Security Code:

The organizer-associated chick homeobox gene, Gnot1, is expressed before gastrulation and regulated synergistically by activin and retinoic acid

Article Abstract:

The chick Gnot1 homeobox gene, a member of the Not gene family, is involved in the formation of the anteroposterior axis and gastrulation process. The epiblast expressing Gnot1 during blastulation is replaced by a localized region in the Hensen's node during gastrulation. The regressing primitive streak, tail bud and notochord express Gnot1 but the neural tube floorplate does not. The increase in expression of Gnot1 in the presence of both activin and retinoic acid is more than that if they are present alone. Cycloheximide also increases the expression of Gnot1.

User Contributions:

Comment about this article or add new information about this topic:

Comment:  (50-4000 characters)

Name:

E-mail:

Security Code: