Direct measurement of in Vivo flux differences between electrophoretic variants of G6PD from Drosophila melanogaster

Article Abstract:

A study was conducted to measure genotype-dependent flux variations using 1-14C and 6-14-C-labeled glucose. The study follows earlier research which applied genotype-dependent interactions and conventional steady-state kinetics in analyzing glucose-6-phosphate dehydrogenase (G6PD). Results show that G6PD(superA) genotype has lower pentose shunt flux than its G6PD(superB) counterpart. The result supports findings that G6PD allozymes create polymorphism for pentose shunt flux.

author: Labate, Joanne, Eanes, Walter F.
Analysis, Genetic polymorphisms, Glucose-6-phosphate dehydrogenase deficiency

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F statistics in Drosophila buzzatii: selection, population size and inbreeding

Article Abstract:

Drosophila buzzatii progenies obtained from rotting cactus cladodes were used to produce additive genetic variance estimates within rots and body size variations between individual rots. Their genotypes at six polymorphic loci were also studied. F(sub ST) estimated from body size data were larger than that obtained from allozyme data, probably due to sellective differentiation of body size. Positive F(sub IS)s are probably due to partial sib mating.

author: Barker, J.S.F., Prout, Timothy
Usage, Variation (Biology), Statistics (Mathematics), Mathematical statistics

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The cross-linking agent hexamethylphosphoramide predominantly induces intra-locus and multi-locus deletions in postmeiotic germ cells of Drosophila

Article Abstract:

Exposure of postmeiotic male germ cells reveals the occurrence of various changes in the characteristic features of DNA sequences in the vermilion locus of Drosophila melanogaster. The changes are in the form of deletions and rearrangement of mutational events. The deletions and rearrangements are stimulated by the cross-linking agent hexamethylphosphoramide (HMPA). The HMPA is identified as vermilion mutations.

author: Aguirrezabalaga, I., Nivard, M.J.M., Comendador, M.A., Vogel, E. W.
Research, Germ cells

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subjects list: Genetic aspects, Drosophila
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