Differential regulation of oocyte maturation and cumulus expansion in the mouse oocyte-cumulus cell complex by site-selective analogs of cyclic adenosine monophosphate

Article Abstract:

Analogs of cyclic adenosine 5'-monophosphate (cAMP) were tested in paired combinations with type I or type II protein kinase isozymes A (PKA) found within the mouse oocyte-cumulus cell complex to determine whether cAMP-dependent protein kinase isozymes influence the response of the complex to cAMP. The potency of the isozymes were characterized according to their ability to prevent germinal vesicle breakdown and to cumulus expansion in response to PKA stimulation.

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Meiotic resumption in response to luteinizing hormone is independent of a Gi family G protein or calcium in the mouse oocyte

Article Abstract:

The relationship between G proteins and luteinizing hormone activated meiotic resumption, during oocyte maturation, is analyzed.

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AMPK regulation of mouse oocyte meiotic resumption in vitro

Article Abstract:

A study on the role of 5-prime-amp-activated protein kinase in oocyte meiotic maturation in mice is presented.

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