Detection of differential gene expression in biofilm-forming versus planktonic populations of Staphylococcus aureus using micro-representational-difference analysis

Article Abstract:

Researchers found that Staphylococcus aureus expresses five genes when it forms a biofilm that are not expressed in the planktonic form. These genes are homologous to threonyl-tRNA synthetase, phosphoglycerate mutase, triosephosphate isomerase, alcohol dehydrogenase I, and ClpC ATPase.

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Very low ethanol concentration affect the viability and growth recovery in post-stationary-phase Staphylococcus aureus populations

Article Abstract:

Growth media for Staphylococcus aureus strain DSM20231with VLEC is supplemented and ultramorphology, growth, and viability compared to those with unsupplemented media for prolonged culture times is determined. These data demonstrate that VLEC have profound effects on the recovery of Staphylococcus aureus even after ethanol depletion and delay the transition from primary to secondary metabolite catabolism.

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Lytic activity of recombinant bacteriophage [phi]11 and [phi]12 endolysins on whole cells and biofilms of Staphylococcus aureus

Article Abstract:

The hydrolysis of heat-killed cells of Staphylococci by recombinant [phi]11 and [phi]12 endolysins is studied. The dissolution of biofilm by the endolysins is found to be the key factor in the accumulation of antibiotics in the cell walls.

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