Article Abstract:
A simulation analysis on a backcross population aimed to identify the influence of marker spacing, gene effect and population size on the strength of marker-quantitative trait loci (QTL) linkage studies and on the standard error of maximum likelihood estimates (MLE) of QTL gene effect and map location. The capacity for detection of a QTL was almost the same for a marker spacing of 10 cM as for an unlimited number of markers and fell very little for marker spacing of 20 or 50 cM.
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Article Abstract:
Pleiotropic models of quantitative genetic variation presents scenarios where genes responsible for the heritability of the character are not eliminated by selection on the character itself. One of these models, the Hill-Keightley, attempts to show that the selection is a result of the unconditionally deleterious effects of the genes that cause heritability. An analysis of the model indicates that selection is compatible with neutral variation of the genes affecting the trait.
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Article Abstract:
A study was conducted to examine quantitative traits with time-dependent measures using a genetic model with additive-dominance effects and genotype and environment interactions. Statistical methods for analyzing conditional genetic effects and conditional genetic variance components were proposed. Conditional variances were estimated by minimum norm quadratic unbiased estimation method.
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