Design and evaluation of useful bacterium-specific PCR primers that amplify genes coding for bacterial 16S rRNA

Article Abstract:

Former primer 63f and reverse primer 1387r were designed to amplify approximately 1,300 bp of a consensus 16S rRNA gene from bacteria. The efficacy and specificity of these two PCR primers were tested by using them to amplify 16 rRNA genes from template DNA taken from a wide range of organisms, including Eubacterium species and organisms from the coryneform and Micrococcus genera. The amplimer pair 63f-1387r was found to be more successful than the amplimer pair 27f-1392r in amplifying the 16S rRNA genes.

author: Fry, John C., Weightman, Andrew J., Marchesi, Julian R., Wade, William G., Sato, Takuichi, Martin, Tracey A., Hiom, Sarah J.
Polymerase chain reaction, Bacterial genetics, Ribosomal RNA, Gene amplification

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Comparing the dehalogenase gene pool in cultivated alpha-halocarboxylic acid-degrading bacteria with the environmental metagene pool

Article Abstract:

The authors describe the study on dehalogenase gene pool in bacteria isolated on dichloropropionic acid. They have investigated the relationship between this gene pool and environmetal metagene pool from which bacteria have been isolated via the use of culture-independent and culture-dependent approaches, and the results demonstrate the existence of a large bias introduced by culturing both in isolated bacteria and in the degradative genes from these bacteria.

author: Weightman, Andrew J., Marchesi, Julian R.
United Kingdom, Analysis, Physiological aspects, Environmental aspects, Biodegradation, Microbiology, Composition, Microbial populations, Carboxylic acids, Microbial ecology

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Molecular evidence for the evolution of metal homeostasis genes by lateral gene transfer in bacteria from the deep terrestrial subsurface

Article Abstract:

Lateral gene transfer (LGT) plays a vital role in increasing the genetic diversity of microorganisms and promoting the spread of fitness-enhancing phenotypes throughout microbial communities. A study is presented in which phylogenetic analyses is used to examine the role of LGT in the evolution of metal homeostasis in subsurface bacteria.

author: Coombs, J. M., Barkay, T.
Phylogeny, Homeostasis, Genetic transformation

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subjects list: Research, Genetic aspects, Bacteria, Biological diversity, Biodiversity
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