Article Abstract:
Research has been conducted on the Gloeophyllum striatum strains. The mechanism of the Fenton-type degradation has been examined.
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Article Abstract:
The ability of the brown rot fungus, Gloeophyllum striatum, to degrade enrofloxacin, a quinolone veterinary antibiotic, is investigated. Mycelia are suspended in solutions containing radio-labeled enrofloxacin and the evolution of radio-labeled carbon dioxide is monitored. As early as one week, detectable amounts of labeled carbon dioxide is present. The degradation pathway is outlined.
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Article Abstract:
Ciprofloxacin, a fluoroquinolone antibacterial agent, undergoes degradation caused by basidiomycetes fungi found in various environments such as agricultural soils and animal dung. This is evident in a study of metabolites generated by the brown rot fungus Gloeophyllum striatum. An analysis of (super 14)CO(sub 2) production from ((super 14))ciprofloxacin in liquid cultures shows that 16 species of basidiomycetes inhabiting soil, humus, wood or animal dung generated up to 35% (super 14)CO(sub 2) during eight weeks of incubation. All species diminished the antibacterial effectiveness of ciprofloxacin in supernatants to between 0 and 33% after 13 weeks despite some low rates of (super 14)CO(sub 2) formation.
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