Article Abstract:
The Cyt1A protein from Bacillus thuringiensis increases the toxicity of Bacillus sphaericus toward Aedes aegypti more than 3,000-fold. This is important because even though B. sphaericus is toxic to Culex and Anopheles mosquitoes, it has little effect on A. aegypti.
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Article Abstract:
Combining Bacillus sphaericus with the Cyt1Ab1 or Cyt2Ba1 cytotoxins from Bacillus thuringiensis can overcome a mosquito's resistance to B. sphaericus alone. This combination suppressed resistance of Culex quinquefasciatus to B. sphaericus from greater than 17,000- to 2-fold.
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Article Abstract:
Various experiments were reported in which separate Culex quinquefasciatus populations were selected for 20 generations to recombinant strains of Bacillus thuringiensis that produced either Cyt1Aa, Cry11Aa, or a 1:3 mixture of these strains. The results indicated that Cyt1Aa is the principal factor responsible for delaying the evolution and expression of resistance to mosquitocidal Cry proteins.
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