Cyt1A from Bacillus thuringiensis synergizes activity of Bacillus sphaericus against Aedes aegypti (Diptera: Culicidae)

Article Abstract:

The Cyt1A protein from Bacillus thuringiensis increases the toxicity of Bacillus sphaericus toward Aedes aegypti more than 3,000-fold. This is important because even though B. sphaericus is toxic to Culex and Anopheles mosquitoes, it has little effect on A. aegypti.

author: Wirth, Margaret C., Federici, Brian A., Walton, William E.

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Cyt1Ab1 and Cyt2Ba1 from Bacillus thuringiensis subsp. medellin and B. thuringiensis subsp. israelensis synergize Bacillus sphaericus against Aedes aegypti and resistant Culex quinquefasciatus (Diptera: Culicidae)

Article Abstract:

Combining Bacillus sphaericus with the Cyt1Ab1 or Cyt2Ba1 cytotoxins from Bacillus thuringiensis can overcome a mosquito's resistance to B. sphaericus alone. This combination suppressed resistance of Culex quinquefasciatus to B. sphaericus from greater than 17,000- to 2-fold.

author: Wirth, Margaret C., Walton, William E., Delecluse, Armelle
Insect pests, Biological insect control, Microbial insecticides

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Cyt1A of Bacillus thuringiensis delays evolution of resistance to Cry11A in the mosquito Culex quinquefasciatus

Article Abstract:

Various experiments were reported in which separate Culex quinquefasciatus populations were selected for 20 generations to recombinant strains of Bacillus thuringiensis that produced either Cyt1Aa, Cry11Aa, or a 1:3 mixture of these strains. The results indicated that Cyt1Aa is the principal factor responsible for delaying the evolution and expression of resistance to mosquitocidal Cry proteins.

author: Wirth, Margaret C., Federici, Brian A., Walton, William E., Hyun-Woo Park
Analysis, Genetic aspects, Growth, Gene expression, Company growth

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subjects list: Research, Bacillus thuringiensis, Control, Mosquitoes, Mosquito control
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