Coronin proteins as multifunctional regulators of the cytoskeleton and membrane trafficking

Article Abstract:

Coronins constitute an evolutionary conserved family of WD-repeat actin-binding proteins, which can be classified into two distinct groups based on their structural features. The molecular mechanisms underlying the regulation of F-actin structures, cytoskeletal rearrangements and intracellular membrane transport by coronin proteins are explored along with the way that they might link cytoskeleton with trafficking in development and diseases.

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Coronin proteins as multifunctional regulators of the cytoskeleton and membrane trafficking

Article Abstract:

Coronins constitute an evolutionary conserved family of WD-repeat actin-binding proteins. Theycan be classified into two distinct groups based on their structural features. The molecular mechanisms underlying the regulation of F-actin structures, cytoskeletal rearrangements and intracellular membrane transport by coronin proteins are explored along with the way that they might link cytoskeleton with trafficking in development and diseases.

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Is sperm capacitation analogous to early phases of Ca(super 2+)-triggered membrane fusion in somatic cells and viruses?

Article Abstract:

An important feature of male fertility is the physiological priming of spermatozoa by a multifaceted process collectively referred to as capacitation. Special emphasis is laid on accumulating evidence suggesting potential similarities between the sperm capacitation and early phases of calcium-triggered membrane fusion during secretary and endocytotic pathways among eukaryotes.

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