Cooperation between C/EBP(alpha) TBP/TFIIB and SWI/SNF recruiting domains is required for adipocyte differentiation

Article Abstract:

Research has been conducted on the chromatin remodeling important for the promoter activation during cellular lineage commitment and differentiation. The ability of the C/EBP(alpha) transcription factor to direct adipocyte uncommitted fibroblast precursor differentiation and to activate the SWI/SNF-dependent myeloid-specific genes has been investigated and the results are reported.

author: Leutz, Achim, Nerlov, Claus, Pedersen, Thomas Askov, Kowenz-Leutz, Elisabeth
Denmark, Germany, Statistical Data Included, Fibroblasts, Fat cells, Adipocytes

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Histone H3 tail positioning and acetylation by the c-Myb but not the v-Myb DNA-binding SANT domain

Article Abstract:

The binding of c-Myb-DNA-binding domain (DBD) to the N-terminal histone tails of H3 and H3.3 is discussed. A function in chromatin organization is displayed by Myb by directing the modifications of histone through its SANT-DBD.

author: Leutz, Achim, Kowenz-Leutz, Elisabeth, Xianming Mo, Laumonnier, Yves, Hong Xu
Science & research, Research, Histones, DNA-ligand interactions, DNA binding

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Heterochromatin: stable and unstable invasion at home and abroad

Article Abstract:

The authors discusses the studies on heterochromatin. The topics of interest include the analysis of different types of heterochromatin and heterochomatin invasion into euchromatin.

author: Baylin, Stephen B., Fahrner, Jill A.
United States, Biological Product (except Diagnostic) Manufacturing, Drugs, Deoxyribonucleic Acid, DNA, Genomes

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subjects list: Analysis, Physiological aspects, Genetic aspects, Chromatin, Gene expression, Genetic research
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