Control of cell lineage-specific development and transcription by bHLH-PAS proteins

Article Abstract:

Progress has been made in what is known about the nature of the basic-helix-loop-helix-PAS (bHLH-PAS) protein subfamily. Ways by which bHLH-PAS proteins regulate lineage-specific gene transcription have been studied. They affect development of the Drosophila CNS midline cells and respiratory system. The bHLH-PAS/Arnt regulatory cassette has implications that relate to evolution. Regulation of cell lineage-specific development has been investigated as has transcription by bHLH-PAS proteins. Underlying mechanisms may exist in invertebrates and vertebrates.

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Spineless provides a little backbone for dendritic morphogenesis

Article Abstract:

The role of the Spineless (Ss) basic helix-loop-helix-PAS (bHLH-PAS) transcription factor in controlling dendrite morphogenesis is described as well as the contributions of other regulatory proteins is reviewed. It is concluded that Ss employs a variety of biochemical mechanisms to control a multiplicity of developmental and physiological processes.

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Genes regulating dendritic outgrowth, branching, and routing in Drosophila

Article Abstract:

The article explores molecular mechanisms controlling dendrite morphogenesis in the embryonic peripheral nervous system of Drosophila. Genes responsible for the dendrite development are described.

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