Comparison of the proteome of Mycobacterium tuberculosis strain H37Rv with clinical isolate CDC 1551

Article Abstract:

Research has been conducted on Mycobacterium tuberculosis strain H37Rv and CDC 1551 genome sequence. The study of the strains' proteomes grown in liquid culture has been carried out in the effort to investigate the difference between the proteomes at protein level, and the resulrs are reported.

author: Dodson, Paul, Betts, Joanna C., Quan, Selwyn, Lewis, Alan P., Thomas, Pam J., Duncan, Ken, McAdam, Ruth A.
Growth, Gel electrophoresis, Genomes, Company growth, Proteomics

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Production of mutants in amino acid biosynthesis genes of Mycobacterium tuberculosis by homologous recombination

Article Abstract:

Results demonstrate that homologous recombination technique generates defined mutants of Mycobacterium tuberculosis. The data show homologous recombination in 11 genes and double-crossover in 4 genes, all involved in the amino acid biosynthesis.

author: Parish, Tanya, Stoker, Neil G., Duncan, Ken, McAdam, Ruth A., Mizrahi, Valerie, Gordhan, Bhavna G.
South Africa, Gene mutations, Gene mutation, Genetic recombination, Biochemical genetics

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Proteome analysis of extracellular proteins regulated by the las and rhl quorum sensing systems in Pseudomonas aeruginosa PAO1

Article Abstract:

Research has been conducted on las and rhl quorum sensing system in Pseudomonas aeruginosa. The authors suggest that it is importane to study the role of quorum sensing system and to identify quorum-sensing system-regulated genes.

author: Whitchurch, Cynthia B., Mattick, John S., Beatson, Scott A., Cordwell, Stuart J., Nouwens, Amanda S., Walsh, Bradley J., Schweizer, Herbert P.
United States, Australia, Genetic regulation, Pseudomonas aeruginosa

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subjects list: United Kingdom, Research, Usage, Physiological aspects, Genetic aspects, Mycobacterium tuberculosis, Microbiology, Bacterial proteins, Analysis
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