Comparison of compositions and metabolic activities of fecal microbiotas in young adults and in antibiotic-treated and non-antibiotic-treated elderly subjects

Article Abstract:

Studies are done to investigate the intestinal microbiota in three different human age groups-healthy young adults, healthy elderly volunteers, and hospitalized elderly patients receiving antibiotics with particular reference to alterations in species diversity together with measurements of their metabolic activities, by analysis of fecal organic acid and ammonia concentrations. The results indicated that the total anaerobe numbers were relatively consistent in old people, however, individual bacterial genera changed markedly with age.

author: Macfarlane, George T., McMurdo, Marion E.T., Macfarlane, Sandra, Woodmansey, Emma J.
Antibiotics, Microbiological research

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Colonization of mucin by human intestinal bacteria and establishment of biofilm communities in a two-stage continuous culture system

Article Abstract:

A study is conducted to determine how intestinal bacteria colonize mucus and to study physiologic and enzymatic factors involved in the destruction of this glycoprotein. Intestinal bacterial populations growing on mucin surfaces are revealed to be phylogenetically and metabolically distinct from their planktonic counterparts.

author: Macfarlane, George T., Macfarlane, Sandra, Woodmansey, Emma J.
Glycoproteins, Bacteria, Mucins

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Degradation of cross-linked and non-cross arabinoxylans by the intestinal microbiota in children

Article Abstract:

The breakdown of ferulic acid-cross-linked AX (AXF) and non-cross-linked AX in children's intestinal microbiotas is investigated, using starch as a readily fermentable polysaccharide for comparative purposes. The results demonstrated that there was variation in the metabolism of these polysaccharides by colonic microbiotas.

author: Macfarlane, George T., Hopkins, Mark J., McBain, Andrew J., Englyst, Hans N., Macfarlane, Sandra, Furrie, Elizabeth
All Other Basic Organic Chemical Manufacturing, Industrial organic chemicals, not elsewhere classified, Polysaccharides, Children, Child health, Nutritional aspects, Gamma oryzanol

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subjects list: Research
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