Comparative sporicidal effects of liquid chemical agents

Article Abstract:

The microbicidal agents sodium hypochlorite, peracetic acid and cupric ascorbate kill almost 99.9% of Bacillus subtilis spores after incubation at 20 degrees centigrade for 30 mins. Glutaraldehyde kills almost 90% spores under the same conditions. Hydrogen peroxide, formaldehyde and phenol are unable to inactivate a significant number of spores. PH, incubation time, dilution and temperature affect the activity of the agents. All the agents have similar activation energy of spore killing but different rates of spore killing.

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Metal-based formulations with high microbicidal activity

Article Abstract:

A comparative investigation was conducted to determine the efficacies of glutaraldehyde, metal ions, chlorine, hydrogen peroxide and formaldehyde as disinfecting agents for bacteria and viruses. The results showed that glutaraldehyde is the most effective disinfectant among the agents tested. However, mixtures of metal ions and peroxide were more effective than glutaraldehyde in inactivating viruses and bacteria. The addition of a metal chelator could enhance the antimicrobial activity of these mixtures.

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Development and testing of a microbiological assay to detect residual effects of disinfectant on hard surfaces

Article Abstract:

Researchers describe an assay that can detect residual disinfectant on surfaces that have been disinfected. This assay showed that surfaces disinfected with chlorine or a commercial disinfectant still exhibited bactericidal activity a week later.

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