Characterization of genes involved in the metabolism of alpha-galactosides by Lactococcus raffinolactis

Article Abstract:

Alpha-galactosidase gene and the genes of Leloir pathway galactose metabolism are organized into aga-galKt operon, which is induced by galactosides. The expression of the operon is modulated by a regulator encoded by galR gene, whose product belongs to the LacI/GalR family of transcriptional regulators. Data indicate that GalR represses the expression of alpha-galactosidase operon leading to a 20-fold reduction in the enzyme activity.

User Contributions:

Comment about this article or add new information about this topic:

Comment:  (50-4000 characters)

Name:

E-mail:

Security Code:

Role of galK and galK in galactose metabolism by Streptococcus thermophilus

Article Abstract:

A transformant of Streptococcus thermophilus SMQ-301 expressing Streptococcus salivarius galK and galM has grown on galactose and has expelled at least twofold less galactose into the medium growth on lactose. The results have shown that the expulsion of galactose by Streptococcus thermophilus LacS has resulted from the inability of Streptococcus thermophilus to rapidly convert [beta]-D-galactose into [alpha]-D-galactose-1-phosphate.

User Contributions:

Comment about this article or add new information about this topic:

Comment:  (50-4000 characters)

Name:

E-mail:

Security Code:

Characterization of genes involved in the metabolism of alpha-galactosides by Lactococcus raffinolactis

Article Abstract:

The galactose metabolism genes conmprising of alpha-galactosidase and Leloir pathway, involving galactokinase and galactose 1-phosphate uridylyltransferase, are organized into an operon, aga-galKT, in Lactococcus raffinolactis. Data indicate that the expression of the aga-galKT operon is modulated by a transcriptional regulator encoded by the galR gene.

User Contributions:

Comment about this article or add new information about this topic:

Comment:  (50-4000 characters)

Name:

E-mail:

Security Code: