Cartilage formation in growth plate and arteries: From physiology to pathology

Article Abstract:

The effects of known or suspected factors that promote chondrogenic differentiation in growth plate and arteries. Some aspects of chondrogenic differentiation of vascular smooth muscle cells (VSMCs), which suggest that a cartilage-like tissue forms in some types of vascular calcifications are highlighted.

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The dual nature of neurotrophins

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Neurotrophins are a small family of dimeric secretory proteins in vertebrate neurons with a broad spectrum of functions. Studies have revealed an intriguing pattern that is neurotrophins can elicit opposing signals utilizing their variable configuration and different receptor types.

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The epigenetic basis for embryonic stem cell pluripotency

Article Abstract:

The different types of model that can explain pluripotency at the level of gene are examined. A novel epigenetic model is proposed to explain how genes are primed in embryonic stem cells to express at later stages of development.

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