Beta-catenin has Wnt-like activity and mimics the Nieuwkoop signaling center in Xenopus dorsal-ventral patterning

Article Abstract:

Molecular evidence suggests that the protein beta-catenin has a role in axis formation during embryonic patterning. Overexpression of the protein in the vegetal ventral region of early cleavage embryos rescued UV-ventralized embryos and caused a dramatic increase in the rate of aggregation of blastomeres. Although it does not enhance gap junction communication, beta-catenin exhibited a behavior highly similar to those of the Wnt gene family, suggesting that it has a signaling instead of a regulatory role during axis formation.

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Frizzled7 mediates canonical Wnt signaling in neural crest induction

Article Abstract:

The role of Frizzled7 receptor in controlling canonical Wnt signaling during the formation of neural crest in Xenopus embryo is studied.

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Dystroglycan is required for proper retinal layering

Article Abstract:

The role of dystroglycan, a transmembrane receptor, during Xenopus retinal development is analyzed.

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