Beta-catenin controls hair follicle morphogenesis and stem cell differentiation in the skin

Article Abstract:

Research has been conducted on the beta-catenin, an important molecule in Wnt/wingless signaling which controls steps in embryogenesis. The role of beta-catenin in skin development has been investigated via the conditional mutation of the epidermis and hair follicle gene and the results indicate that beta-catenin mutation has blocked placode formation which generates hair follicles.

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A conserved regulatory system for aging

Article Abstract:

The author reviews the publications on the aging regulation. The topics of interest include the effect of gene mutations on the lifespan extension and the analysis of the conserved system which regulates the lifespan and which may have arisen early in the evolution..

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Genetic interaction between Wnt/beta-catenin and BMP receptor signaling during formation of the AER and the dorsal-ventral axis in the limb

Article Abstract:

Research has been conducted on beta-catenin. The authors report that beta-catenin is a regulator of apical ectodermal ridge and limb dorsal-ventral axis formations.

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