"Best Friends" Sharing the HMGA1 Gene: Comparison of the Human and Canine HMGA1 to Orthologous Other Species

Article Abstract:

Chromosomal aberrations and overexpression of HMGA1 are discussed with regard to malignant tumor formation. Comparisons are made between canine, human, rat, hamster, murine, bovine, chicken, pig, and Xenopus HMGA1 transcripts.

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RAS Gene Hot-Spot Mutations in Canine Neoplasias

Article Abstract:

Screening was performed on 11 canine melanomas and 13 fibrosarcomas to determine point mutations in canine neoplasias. Findings regarding the role of RAS genes are compared to current data from other tumor studies.

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Establishment of a Cell Line Derived from a Canine Prostate Carcinoma with a Highly Rearranged Karyotype

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A cell line is established for a canine prostate adenocarcinoma, drawn from a collected tumor sample. Findings show a highly rearranged karyotype with a large biarmed marker; further details are provided.

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