Bacteriophage migration via nematode vectors: Host-parasite-consumer interactions in laboratory microcosms

Article Abstract:

A tractable model for studying pathogen-host-vector biology is presented to demonstrate that Caenorhabditis elegans nematodes are able to transmit phage from infected to uninfected bacterial populations. The results indicate that virus transmission increases with worm density and host bacterial abundance, however, transmission decreases with initial phage abundance, perhaps as viruses eliminate available hosts before migration could occur.

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Experimental examination of bacteriophage latent-period evolution as a response to bacterial availability

Article Abstract:

The impact of phage generation time on the population growth of actively infecting obligately lytic phage, particularly as latent periods varies between phage mutants and their wild-type (WT) parent is emphasized. The observations suggest that phage displaying very short latent periods may be viewed as specialists for propagation when bacteria within cultures are highly prevalent and transmission between cultures is easily accomplished.

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Endopeptidase and glycosidase activities of the bacteriophage B30 lysin

Article Abstract:

Endolysins have been found to be capable of cleaving most bonds in peptidoglycan. Study is presented to show that the minimum peptide sequence necessary in a substrate for the phage B30 lysin is DL-gamma-Glu-Lys-D-Ala-Ala-Ala.

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