Androgen regulation of a laryngeal-specific myosin heavy chain mRNA isoform whose expression is sexually differentiated

Article Abstract:

Androgen controls the expression of the laryngeal-specific myosin heavy chain responsible for the fast twitch in the laryngeal muscles (LM) of male Xenopus laevis frogs. Females express LM in a few fast-twitch muscle fibres. The number of muscle fibres expressing LM and the expression of LM increases in juvenile females treated with androgen. In juvenile males all the muscle fibres express LM and the expression increases on treatment with androgen. Castrated males show a decrease in the expression of LM. Androgen probably activates the large number of its receptors present in the larynx.

author: Kelley, Darcy B., Catz, Diana S., Fisherm, Leslie M.
Growth, Muscles, Xenopus, Androgens, Endocrinology, Sex differentiation, Larynx

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Light and developmental regulation of the gene con-10 of Neurospora crassa

Article Abstract:

Transformation and homologous recombination help integrate a translational fusion of con-10 with Escherichia coli lacZ at the his 3 locus of Neurospora crassa. Experimental studies on these constructs help identify genetic segments essential for normal light and developmental expression of con-10. Maximum con-10 expression requires two copies of a 17-bp enhancer sequences and binding is observed between the protein associated with the extracts of vegetative mycelia and conidia with this enhancer sequence.

author: Ebbole, Daniel J., Corrochano, Luis M., Lauter, Frank-Roman, Yanofsky, Charles
Analysis, Developmental biology, Light

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Keeping pace with Neurospora circadian rhythms

Article Abstract:

The filamentous fungus 'Neurospora crassa' is popular among microbiologists as the basis for studying the molecular components of circadian rhythmicity. Neurospora's biological clock is primarily composed of the frq transcription/translation-feedback loop and genes such as the 'white collar-1' and 'white collar-2.' This fungi is considered as an excellent prototype for evaluating three major areas of clock research.

author: Bell-Pedersen, Deborah
Circadian rhythms

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subjects list: Physiological aspects, Genetic aspects, Neurospora
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