An archael pathogen

Article Abstract:

A long-held belief that human pathogens are mostly bacteria and eukaryotes is refuted, since recent studies have indicated presence of archael sequences in infected dental root canals. Healthy root canals are sterile environments and microbes that penetrate this must be having some pathogenic features, however, it is still not clear whether the Archaea were participating in the disease process or whether they were in the root canal because disease created the conditions suitable for their growth.

author: Perkel, Jeffrey M.
Polymerase chain reaction, Archaeabacteria, Tooth diseases, Archaea

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Give P2P a chance

Article Abstract:

Peer-to-peer (P2P) networking was attacked by the entertainment industry for its use in pirating copyright material, however, P2P can prove useful if some guidelines are followed. P2P can be used to share data, to create pooled image libraries, disseminate genomic scale datasets and share publications and this can be achieved if P2P software enables scheduled searching, addressing copyright issues, giving editing access to trusted people and integrating with other P2P networks.

author: Perkel, Jeffrey M.
On-Line Information Services, Videotex & Teletext, Evaluation, Online services, Online information services, Information services, Online information service, Client/server architecture, Peer to peer computing, Peer to peer networking

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The scientific do-over

Article Abstract:

Arul Chinnaiyan coauthored 16 books between 1995 and 1998 including those describing identification of apoptotic signaling pathway members, FADD and FLICE. He feels if he had the modern technology at that period of time, he would save lot of time, which he could use to expand his work including microarrays and RNAi tools, enabling him survey protein's role in the cell, rather than limiting himself to apoptotic pathways.

author: Perkel, Jeffrey M.
Executive changes & profiles, Michigan, Officials and employees, Beliefs, opinions and attitudes, Technology application, Protein research, University of Michigan, DNA microarrays, RNA interference, Chinnaiyan, Arul

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subjects list: Research, United States, Analysis, Usage
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