Adult cardiac stem cells are multipotent and support myocardial regeneration

Article Abstract:

Research demonstrates that a subpopulation of replicating myocytes in adult heart possess properties of cardiac stem cells. Data indicate that they self-renew, clonogenic, and multipotent and produce myocytes, smooth muscle, and endothelial cells. These stem cells when injected into an ischemic heart are able to reconstitute well-differentiated myocardium.

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Canadian stem cells scientists take the prize

Article Abstract:

The recipients of the Lasker Award for Basic Medical Research in 2005 are Ernest A. McCulloch and James E. Till. The landmark studies of McCulloch and Till in the 1960s defined the hallmark properties of stem cells, the ability to self-renew and differentiate.

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Multi-organ, multi-lineage engraftment by a single bone marrow-derived stem cell

Article Abstract:

Research shows that during bone marrow homing, the rare hematopoietic stem cells show an increase in the expression of CD34 and SCA-1. Data indicate that such adult bone marrow cells can differentiate into epithelial cells of various organs and tissues.

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