Adaptation of Pseudomonas sp. strain 7-6 to quaternary ammonium compounds and their degradation via dual pathways

Article Abstract:

Pseudomonas sp. strain 7-6, isolated from active sludge, has utilized n-dodecyltrimethylammonium chloride (DTAC), a quaternary ammonium surfactant, as a sole carbon, nitrogen and energy source. Two pathways, pathway 1 and pathway 2, were proposed by gas chromatography-mass spectrometry analysis for DTAC metabolism and were found that pathway 1 was the main pathway for the degradation of DTAC.

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The metabolic pathway of 4-aminophenol in Burkholderia sp. strain AK-5 differs from that of aniline and aniline with C-4 substituents

Article Abstract:

Research has been conducted on Burkholderia sp. strain AK-5 which utilizes 4-aminophenol. The authors discuss the pathway for the 4-aminophenol metabolism in this strain which is based on the metabolite identification carried out via the use of gas chromatography-mass spectrometry analysis.

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Circumventing the effect of product toxicity: Development of a novel two-stage production process for the Lantibiotic gallidermin

Article Abstract:

A novel overproduction strategy for type A lantibiotics gallidermin precursor based on the elimination of their self-toxicity is presented.

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